Washington University in St. Louis

The Patti Lab
Metabolomics to elucidate novel biochemical mechanisms of disease
Job Opportunities
Job opportunities are available.

Metabolomics: The Apogee of the Omic Triology

Patti GJ, Yanes O, Siuzdak G
Metabolomics: The Apogee of the Omic Triology
Nature Reviews, 13(4), 263-269, 2012
doi:10.1038/nrm3314

Metabolites, the chemical entities that are transformed during metabolism, provide a functional readout of cellular biochemistry. With emerging technologies in mass spectrometry, thousands of metabolites can now be quantitatively measured from minimal amounts of biological material, which has thereby enabled systems-level analyses. By performing global metabolite profiling, also known as untargeted metabolomics, new discoveries linking cellular pathways to biological mechanism are being revealed and are shaping our understanding of cell biology, physiology and medicine.

Washington University, Departments of Chemistry, Genetics, and Medicine. Saint Louis, Missouri 63110 USA